Second Messenger
Second Messenger Animation
The binding of ligands (“first messengers”) to many cellsurface receptors leads to a short-lived increase (or decrease) in the concentration of certain low-molecular- weight intracellular signaling molecules termed second messengers. These molecules include 3',5'-cyclic AMP (cAMP), 3',5'- cyclic GMP (cGMP), 1,2-diacylglycerol (DAG), and inositol 1,4,5-trisphosphate (IP3). Other important second messengers are Ca2 and various inositol phospholipids, also called phosphoinositides, which are embedded in cellular membranes.
The elevated intracellular concentration of one or more second messengers following binding of an external signaling molecule triggers a rapid alteration in the activity of one or more enzymes or nonenzymatic proteins. In muscle, a signalinduced rise in cytosolic Ca2 triggers contraction. A similar increase in Ca2 induces exocytosis of secretory vesicles in endocrine cells and of neurotransmitter containing vesicles in nerve cells.
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HCV Seroconversion Panel Donor# 63792
Select Currency //1,181.00HCV Seroconversion Panels are intended for use by diagnostic manufacturers, researchers, and clinical laboratories to develop, evaluate, and/or troubleshoot new and existing assays. The panels contain characterized samples with comprehensive data which...HCV6220Select Currency //1,181.00 -
Zika Virus Seroconversion Panel
Select Currency //2,852.00Zika Virus Seroconversion Panel - 7 X 0.5 mLKZMC047Select Currency //2,852.00 -
HIV Seroconversion Panel Donor# 79065
Select Currency //2,360.00HIV Seroconversion Panel Donor# 79065 - 5 X 1 mLHIV9078Select Currency //2,360.00 -
HIV Seroconversion Panel Donor# 77840
Select Currency //1,838.00HIV Seroconversion Panel Donor# 77840 - 4 X 1 mLHIV9082Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 77600
Select Currency //1,838.00HIV Seroconversion Panel Donor# 77600 - 4 X 1 mLHIV9084Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 75062
Select Currency //2,360.00HIV Seroconversion Panel Donor# 75062 - 15 X 1 mLHIV9079Select Currency //2,360.00 -
HIV Seroconversion Panel Donor# 75018
Select Currency //2,360.00HIV Seroconversion Panel Donor# 75018 - 23 X 1 mLHIV9077Select Currency //2,360.00 -
HIV Seroconversion Panel Donor# 73698
Select Currency //2,360.00HIV Seroconversion Panel Donor# 73698 - 13 X 1 mL Donor Demographics: Donor source plasma was collected from a U.S. licensed blood collection facility. Donor was un-treated and asymptomatic throughout the collection period. Notes on Data:1. This panel...HIV12008Select Currency //2,360.00 -
HIV Seroconversion Panel Donor# 73695
Select Currency //2,360.00HIV Seroconversion Panel Donor# 73695 - 9 X 1 mLHIV12007Select Currency //2,360.00 -
HIV Seroconversion Panel Donor# 68582
Select Currency //1,838.00HIV Seroconversion Panel Donor# 68582 - 16 X 1 mLHIV9030Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 68262
Select Currency //1,838.00HIV Seroconversion Panel Donor# 68262 - 12 X 1 mLHIV9029Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 68205
Select Currency //1,838.00HIV Seroconversion Panel Donor# 68205 - 7 X 1 mLHIV9026Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 67996
Select Currency //1,838.00HIV Seroconversion Panel Donor# 67996 - 12 X 1 mLHIV9025Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 67860
Select Currency //1,838.00HIV Seroconversion Panel Donor# 67860 - 7 X1 mLHIV9028Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 67706
Select Currency //1,838.00HIV Seroconversion Panel Donor# 67706 - 22 X 1 mLHIV9023Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 67512
Select Currency //1,838.00HIV Seroconversion Panel Donor# 67512 - 22 X 1 mLHIV9020Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 67485
Select Currency //1,838.00HIV Seroconversion Panel Donor# 67485 - 17 X 1 mLHIV9021Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 66686
Select Currency //1,838.00HIV Seroconversion Panel Donor# 66686 - 16 X 1 mLHIV9033Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 66632
Select Currency //1,838.00HIV Seroconversion Panel Donor# 66632 - 13 X 1 mLHIV9034Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 66575
Select Currency //1,838.00HIV Seroconversion Panel Donor# 66575 - 10 X 1 mLHIV9018Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 66048
Select Currency //1,838.00HIV Seroconversion Panel Donor# 66048 - 19 X 1 mLHIV9031Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 65790
Select Currency //1,838.00HIV Seroconversion Panel Donor# 65790 - 10 X 1 mLHIV9016Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 65685
Select Currency //1,838.00HIV Seroconversion Panel Donor# 65685 - 3 X 1 mLHIV9019Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 65522
Select Currency //1,838.00HIV Seroconversion Panel Donor# 65522 - 5 X 1 mLHIV9014Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 65404
Select Currency //1,838.00HIV Seroconversion Panel Donor# 65404 - 7 X mLHIV9013Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 65389
Select Currency //1,838.00HIV Seroconversion Panel Donor# 65389 - 8 X 1 mLHIV9012Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 65376
Select Currency //1,838.00HIV Seroconversion Panel Donor# 65376 - 6 X 1 mLHIV9089Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 64954
Select Currency //1,838.00HIV Seroconversion Panel Donor# 64954 - 11 X 1 mLHIV9011Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 64578
Select Currency //1,838.00HIV Seroconversion Panel Donor# 64578 - 8 X 1 mLHIV9022Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 64469
Select Currency //1,838.00HIV Seroconversion Panel Donor# 64469 - 12 X 1 mLHIV9024Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 63753
Select Currency //2,360.00HIV Seroconversion Panel Donor# 63753 - 9 X 1 mLHIV9076Select Currency //2,360.00 -
HIV Seroconversion Panel Donor# 63331
Select Currency //1,838.00HIV Seroconversion Panel Donor# 63331 - 7 X 1 mLHIV6248Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 63215
Select Currency //2,360.00HIV Seroconversion Panel Donor# 63215 - 4 X 1 mLHIV9081Select Currency //2,360.00 -
HIV Seroconversion Panel Donor# 62216
Select Currency //2,360.00HIV Seroconversion Panel Donor# 62216 - 4 X 1 mLHIV9075Select Currency //2,360.00 -
HIV Seroconversion Panel Donor# 61694-74
Select Currency //1,838.00HIV Seroconversion Panel Donor# 61694-74 - 13 X 1 mLHIV6244Select Currency //1,838.00 -
HIV Seroconversion Panel Donor# 1043487
Select Currency //1,838.00HIV Seroconversion Panel Donor# 1043487 - 6 X 1 mLHIV9096Select Currency //1,838.00 -
HIV Pre/Post Seroconversion Panel Donor# 67101
Select Currency //740.00HIV Pre/Post Seroconversion Panel Donor# 67101 - 3 X 1 mLHIV10234Select Currency //740.00 -
HCV Seroconversion Panel Donor# 90163052
Select Currency //1,838.00HCV Seroconversion Panel Donor# 90163052 - 7 X 1 mLHCV10071Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 72237
Select Currency //1,838.00HCV Seroconversion Panel Donor# 72237 - 9 X 1 mLHCV10165Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 70225
Select Currency //1,838.00HCV Seroconversion Panel Donor# 70225 - 5 X 1 mLHCV10185Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 69654
Select Currency //1,242.00HCV Seroconversion Panel Donor# 69654 - 7 X 1 mLHCV10002Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 69263
Select Currency //1,242.00HCV Seroconversion Panel Donor# 69263 - 10 X 1 mLHCV10008Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 69158
Select Currency //1,242.00HCV Seroconversion Panel Donor# 69158 - 13 X 1 mLHCV10003Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 69142
Select Currency //1,242.00HCV Seroconversion Panel Donor# 69142 - 8 X 1 mLHCV10019Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 69089
Select Currency //1,242.00HCV Seroconversion Panel Donor# 69089 - 10 X 1 mLHCV10000Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 69028
Select Currency //1,242.00HCV Seroconversion Panel Donor# 69028 - 6 X 1 mLHCV10004Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 68896
Select Currency //1,242.00HCV Seroconversion Panel Donor# 68896 - 6 X 1 mLHCV10009Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 68744
Select Currency //1,242.00HCV Seroconversion Panel Donor# 68744 - 13 X 1 mLHCV10020Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 68629
Select Currency //1,242.00HCV Seroconversion Panel Donor# 68629 - 10 X 1 mLHCV10033Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 68628
Select Currency //1,242.00HCV Seroconversion Panel Donor# 68628 - 12 X 1 mLHCV10016Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 68470
Select Currency //1,242.00HCV Seroconversion Panel Donor# 68470 - 14 X 1 mLHCV10021Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 68450
Select Currency //1,242.00HCV Seroconversion Panel Donor# 68450 - 11 X 1 mLHCV10022Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 68223
Select Currency //1,242.00HCV Seroconversion Panel Donor# 68223 - 13 X 1 mLHCV10036Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 68157
Select Currency //1,242.00HCV Seroconversion Panel Donor# 68157 - 4 X 1 mLHCV10014Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 67861
Select Currency //1,242.00HCV Seroconversion Panel Donor# 67861 - 12 X 1 mLHCV10052Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 67787
Select Currency //1,242.00HCV Seroconversion Panel Donor# 67787 - 14 X 1 mLHCV10051Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 67766
Select Currency //1,242.00HCV Seroconversion Panel Donor# 67766 - 15 X 1 mLHCV10050Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 67539
Select Currency //1,242.00HCV Seroconversion Panel Donor# 67539 - 16 X 1 mLHCV10029Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 67505
Select Currency //1,242.00HCV Seroconversion Panel Donor# 67505 - 21 X 1 mLHCV10023Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 67391
Select Currency //1,838.00HCV Seroconversion Panel Donor# 67391 - 12 X 1 mLHCV10026Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 67356
Select Currency //1,242.00HCV Seroconversion Panel Donor# 67356 - 10 X 1 mLHCV10013Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 67355
Select Currency //1,242.00HCV Seroconversion Panel Donor# 67355 - 11 X 1 mLHCV10007Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 67116
Select Currency //1,242.00HCV Seroconversion Panel Donor# 67116 - 7 X 1 mLHCV10028Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 66861
Select Currency //1,838.00HCV Seroconversion Panel Donor# 66861 - 11 X 1 mLHCV9057Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 66801
Select Currency //1,242.00HCV Seroconversion Panel Donor# 66801 - 11 X 1 mLHCV10025Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 66751
Select Currency //1,242.00HCV Seroconversion Panel Donor# 66751 - 8 X 1 mLHCV10027Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 66747
Select Currency //1,242.00HCV Seroconversion Panel Donor# 66747 - 13 X 1 mLHCV10012Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 66732
Select Currency //1,838.00HCV Seroconversion Panel Donor# 66732 - 11 X 1 mLHCV9055Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 66719
Select Currency //1,242.00HCV Seroconversion Panel Donor# 66719 - 8 X 1 mLHCV10024Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 66666
Select Currency //1,242.00HCV Seroconversion Panel Donor# 66666 - 13 X 1 mLHCV10011Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 66647
Select Currency //1,838.00HCV Seroconversion Panel Donor# 66647 - 5 X 1 mLHCV9058Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 66626
Select Currency //1,838.00HCV Seroconversion Panel Donor# 66626 - 8 X 1 mLHCV9054Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 66158
Select Currency //1,838.00HCV Seroconversion Panel Donor# 66158 - 13 X 1 mLHCV9050Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 66113
Select Currency //1,242.00HCV Seroconversion Panel Donor# 66113 - 16 X 1 mLHCV10032Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 66074
Select Currency //1,242.00HCV Seroconversion Panel Donor# 66074 - 5 X 1 mLHCV10045Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 65982
Select Currency //1,242.00HCV Seroconversion Panel Donor# 65982 - 4 X 1 mLHCV10044Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 65977
Select Currency //1,242.00HCV Seroconversion Panel Donor# 65977 - 8 X 1 mLHCV10030Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 65643
Select Currency //1,242.00HCV Seroconversion Panel Donor# 65643 - 10 X 1 mLHCV10043Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 65470
Select Currency //1,242.00HCV Seroconversion Panel Donor# 65470 - 7 X 1 mLHCV10010Select Currency //1,242.00 -
HCV Seroconversion Panel Donor# 65064
Select Currency //1,838.00HCV Seroconversion Panel Donor# 65064 - 16 X 1 mLHCV10017Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 64766
Select Currency //1,181.00HCV Seroconversion Panel Donor# 64766 - 5 X 1 mLHCV9049Select Currency //1,181.00 -
HCV Seroconversion Panel Donor# 64437
Select Currency //1,181.00HCV Seroconversion Panel Donor# 64437 - 8 X 1 mLHCV9048Select Currency //1,181.00 -
HCV Seroconversion Panel Donor# 64273
Select Currency //1,838.00HCV Seroconversion Panel Donor# 64273 - 10 X 1 mLHCV9047Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 64254
Select Currency //1,838.00HCV Seroconversion Panel Donor# 64254 - 5 X 1 mLHCV9046Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 64150
Select Currency //1,838.00HCV Seroconversion Panel Donor# 64150 - 8 X 1 mLHCV9045Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 63911
Select Currency //1,838.00HCV Seroconversion Panel Donor# 63911 - 6 X 1 mLHCV9044Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 63869
Select Currency //1,181.00HCV Seroconversion Panel Donor# 63869 - 6 X 1 mLHCV9043Select Currency //1,181.00 -
HCV Seroconversion Panel Donor# 63625
Select Currency //1,838.00HCV Seroconversion Panel Donor# 63625 - 8 X 1 mLHCV9041Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 63318
Select Currency //1,838.00HCV Seroconversion Panel Donor# 63318 - 7 X 1 mLHCV6227Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 63135
Select Currency //1,838.00HCV Seroconversion Panel Donor# 63135 - 12 X 1 mLHCV6226Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 62999
Select Currency //1,838.00HCV Seroconversion Panel Donor# 62999 - 19 X 1 mLHCV6225Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 62886
Select Currency //1,838.00HCV Seroconversion Panel Donor# 62886 - 12 X 1 mLHCV6228Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 62804
Select Currency //1,838.00HCV Seroconversion Panel Donor# 62804 - 8 X 1 mLHCV6229Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 62680
Select Currency //1,838.00HCV Seroconversion Panel Donor# 62680 - 6 X 1 mLHCV6224Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 62507
Select Currency //1,181.00HCV Seroconversion Panel Donor# 62507 - 22 X 1 mLHCV6223Select Currency //1,181.00 -
HCV Seroconversion Panel Donor# 62286
Select Currency //1,838.00HCV Seroconversion Panel Donor# 62286 - 8 X 1 mLHCV6222Select Currency //1,838.00 -
HCV Seroconversion Panel Donor# 62258
Select Currency //1,181.00HCV Seroconversion Panel Donor# 62258 - 8 X 1 mLHCV6221Select Currency //1,181.00 -
HCV Seroconversion Panel Donor# 61251
Select Currency //1,181.00HCV Seroconversion Panel Donor# 61251 - 8 X 1 mLHCV6218Select Currency //1,181.00 -
HCV Seroconversion Panel Donor# 61025
Select Currency //1,181.00HCV Seroconversion Panel Donor# 61025 - 5 X 1 mLHCV6217Select Currency //1,181.00 -
HCV Seroconversion Panel Donor# 60749
Select Currency //1,181.00HCV Seroconversion Panel Donor# 60749 - 14 X 1 mLHCV6219Select Currency //1,181.00