Description
Product Overwiew:
Recombinant Human IFN alpha 2 Protein (Interferon alpha-2) expressed in Yeast.
Background:
Human interferon alpha-2 (IFNα2) is a cytokine belonging to the family of type I IFNs. IFNα2 is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection. The first description of IFNs as a cellular agent interfering with viral replication was made by Alick Isaacs and Jean Lindenmann in 1957. The history of this finding was recently reviewed. There are 3 types of IFNs: Interferon type I, Interferon type II and Interferon type III. The type II IFN, also called IFNγ, is produced by specific cells of the immune system. Unlike type I and type III IFNs, IFNγ has only a modest role in directly restricting viral infections. Type I and type III IFNs act similarly. However, the action of type III IFNs, also known as IFNλ, is limited to epithelial cells while type I IFNs act on all body's cells.
Host:
N/A
Sequence:
Amino acid sequence derived from human IFNA2 (NP_000596.2) (Cys24-Glu188) was expressed.
Reactivity:
N/A
Application:
N/A
Used for:
N/A
Kit components:
N/A
Features & Benefits:
N/A
Usage Notes:
Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human IFN alpha 2 protein in sterile ddH2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Storage buffer:
N/A
Storage instructions:
Lyophilized Human IFN alpha 2 protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Shipping:
The product is shipped at ambient temperature.
Precaution:
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.