ABM Knockout Cell Line

abm | Araf CRISPR Knocked out RAW264.7 Stable cell Cell Line (Mouse) T3-3 | T9529Araf Stable Knockout Mouse RAW264.7 Cell Line is established via CRISPR/Cas9 mediated frameshift mutation of the Araf...

abm | Araf CRISPR Knocked out RAW264.7 Stable cell Cell Line (Mouse) T1-19 | T9511Araf Stable Knockout Mouse RAW264.7 Cell Line is established via CRISPR/Cas9 mediated frameshift mutation of the...

abm | NLK Stable Knockout Human A549 Cell Line | T9510NLK Stable Knockout Human A549 Cell Line is established via CRISPR/Cas9 mediated frameshift mutation of the NLK gene (NM_016231) using the...

abm | LIN28B Stable Knockout Human A2780 Cell Line | T9506LIN28B Stable Knockout Human A2780 Cell Line is established via CRISPR/Cas9 mediated frameshift mutation of the LIN28B gene (NM_001004317)...

abm | FRK Stable Knockout Human H1299 Cell Line | T9505FRK Stable Knockout Human H1299 Cell Line is established via CRISPR/Cas9 mediated frameshift mutation of the FRK gene (NM_002031) using the...

abm | JWA Stable Knockout Human MHCC97L Cell Line | T9504JWA Stable Knockout Human MHCC97L Cell Line is established via CRISPR/Cas9 mediated frameshift mutation of the JWA gene (NM_006407) using the...

abm | FLNC Stable Knockout Human A2780 Cell Line | T9503FLNC Stable Knockout Human A2780 Cell Line is established via CRISPR/Cas9 mediated frameshift mutation of the FLNC gene (NM_001458) using the...

abm | GAB1 Stable Knockout Human 8505c Cell Line | T9501GAB1 Stable Knockout Human 8505c Cell Line is established via CRISPR/Cas9 mediated frameshift mutation of the GAB1 gene (NM_002039) using the...

abm | ATG5 Stable Knockout HEK293 Cell Line | T6438Biosafety:IIOrganism:Human (H. sapiens)Source Organ:KidneyGrowth Properties:AdherentMorphology:EpithelialClones:N/APassage Number:<

abm | GOT2 Knockout Stable HEK293 Cell Line (Clone A7) | T6426CRISPR/Cas9 was used to introduce a disruption of the GOT2 gene in HEK293 cells. The resulting CRISPR/Cas9 GOT2-knockout HEK293 cell...

abm | GOT2 Knockout Stable HEK293 Cell Line (Clone A6) | T6425CRISPR/Cas9 was used to introduce a disruption of the GOT2 gene in HEK293 cells. The resulting CRISPR/Cas9 GOT2-knockout HEK293 cell...

abm | GOT2 Knockout Stable HEK293 Cell Line (Clone A3) | T6424CRISPR/Cas9 was used to introduce a disruption of the GOT2 gene in HEK293 cells. The resulting CRISPR/Cas9 GOT2-knockout HEK293 cell...

abm | PIWIL1 Knockout Stable AGP01 Cell Line | T6410PIWIL1 was knocked out of the AGP01 cells via CRISPR/Cas9. May be used to study the potential functions of the PIWIL1 gene...

abm | TP53 Stable Knockout K9 Fetus 1 Cell Line | T6405TP53 was knocked out of the K9 Fetus 1 cells via CRISPR/Cas9. May be used as a cellular system to examine novel oncogenic functions, and...

abm | MCT4 Knockout PC-3 Cell Line | T6328 Biosafety:IIOrganism:N/ASource Organ:N/AGrowth Properties:AdherentMorphology:N/AClones:N/APassage Number:N/APopulation Do

abm | COX10 Stable Knockout Mouse Fibroblast Cell Line | T6303To generate the COX10 Stable Knockout Mouse Fibroblast Cell Line, a primary skin fibroblast culture was established from a knockin mouse...

abm | KtyI Stable Knockout Mouse Keratinocyte Cell Line | T6293KtyI Stable Knockout Mouse Keratinocyte Cell Line was derived from mice lacking keratins and was spontaneously immortalized. The lack...

abm | ACΔ3-6 Stable Knockout HEK293 Cell Line | T6291AC3 and AC6 encoded by the ADCY3 and ADCY6 genes, are the most abundant adenylyl cyclase (AC) isoforms in HEK293 cells. ACΔ3/6 Stable Knockout...

abm | BVRA Stable Knockout Hepa1c1c7 Cell Line | T6282BVRA (biliverdin reductase A) was knocked out of the mouse Hepa1c1c7 cells using sgRNAs inserted into the GuideIt-zsGreen plasmid. The plasmid...

abm | BVRA Stable Knockout MCT Cell Line | T6281BVRA (biliverdin reductase A) was knocked out of the mouse proximal tubule cells (MCT) using sgRNAs inserted into the GuideIt-zsGreen plasmid. The...

abm | Gnpat Stable Knockout Mouse Myoblast (14.11) Cell Line | T6279Cells were isolated from cross-breed pups of Gnpat Knockout mice (Gnpat tm1Just) crossed with SV40 carrying Tg(H2‐K1‐tsA58)11Kio...

abm | Gnpat Stable Knockout Mouse Myoblast (21.15) Cell Line | T6278Cells were isolated from cross-breed pups of Gnpat Knockout mice (Gnpattm1Just) crossed with SV40 carrying Tg(H2‐K1‐tsA58)11Kio...

abm | IFN-α-β Stable Knockout Macrophage Cell Line | T6238Biosafety:IIOrganism:MouseSource Organ:Bone MarrowGrowth Properties:AdherentMorphology:RoundClones:N/APassage Number:N/A<

abm | NOD1 Stable Knockout AGS (41H8) Cell Line | T6188CRISPR/Cas9 gene editing was used to generate NOD1 KO clones. For this, AGS cells were transformed with vectors expressing “Cas9 nickase”...

abm | NOD1 Stable Knockout AGS (41A8) Cell Line | T6187CRISPR/Cas9 gene editing was used to generate NOD1 KO clones. For this, AGS cells were transformed with vectors expressing “Cas9 nickase”...

abm | PTEN Stable Knockout MEF Cell Line | T6179PTEN Stable Knockout MEF Cell Linewere established via the 3T9 protocol, and the expression of PTEN was knocked out. MEF cells were derived from...

abm | Pax6 KnockOut U251N Cell Line | T6167CRISPR-Cas9 was utilized to knockout PAX6 from the U251N cells to establish Pax6 KnockOut U251N Cell Line (2.10 KO cells). Knockout was verified via...

abm | ADRM1 Stable Knockout HCT116 (Clone B11) Cell Line | T6162ADRM1 or Adhesion regulating molecule 1, is a component of the proteosome and ubiquitin receptor that recruits the deubiquitinating...

abm | CBFβ Stable Knockout HepG2 Cell Line | T6161CBFβ is the non-DNA-binding subunit of the core binding factor (CBF) transcription factor. Derived from HepG2 cells, CBFβ was knocked out using...

abm | APPL1 Stable Knockout MEF Cell Line | T6158APPL1 Stable Knockout MEF Cell Line was derived from E13.5 mouse embryo which had been cross-bred to express null APPL1. May be used alongside with...

abm | RNH1 Stable Knockout K562 Cell Line | T6157Biosafety:IIOrganism:HumanSource Organ:Bone marrowGrowth Properties:SuspensionMorphology:RoundClones:N/APassage Number:N/A<

abm | PD-L1 Knockout Stable NBK Cell Line | T6156Biosafety:IIOrganism:N/ASource Organ:N/AGrowth Properties:N/AMorphology:EpithelialClones:N/APassage Number:N/APopul

abm | GALK2 Stable Knockout HEK293T Cell Line | T6154The Galactokinase 2 (GALK2) is an efficient kinase of N-acetylgalactosamine in primary pathway for galactose metabolism the Leloir pathway that...

abm | GALK1 Stable Knockout HEK293T Cell Line | T6153The Galactokinase 1 (GALK1) is major enzyme in the Leloir pathway, the primary pathway for galactose metabolism. Specifically, this enzyme...

abm | GALK2+GALE Stable Knockout HEK293T Cell Line | T6152The UDP-galactose-4 epimerase (encoded by GALE) and Galactokinase 2 (GALK2) are both major enzymes in the Leloir pathway, the primary...

abm | GALK1+GALE Stable Knockout HEK293T Cell Line | T6151The UDP-galactose-4 epimerase (encoded by GALE) and Galactokinase 1 (GALK1) are both major enzymes in the the Leloir pathway, the primary...

abm | GALE Stable Knockout HEK293T (Clone 4) Cell Line | T6150The GALE gene encodes UDP-galactose-4 epimerase which operates in the Leloir pathway, the primary pathway for galactose metabolism. This...

abm | SP100 Stable Knockout HEp-2 Cell Line | T6135Nuclear domain 10 (ND10) bodies are membrane-less cellular components found in the nucleus that affect transcription and are implicated in some...

abm | p47phox Stable Knockout Mouse Aortic Endothelial (iMAEC-p47) Cell Line | T3181Immortalization using polyoma middle-sized T-antigen (PmT) methodBiosafety:IIOrganism:MouseSource...

abm | eNOS Stable Knockout Mouse Aortic Endothelial (iMAEC-eNOS) Cell Line | T3180The eNOS Stable Knockout Mouse Aortic Endothelial (iMAEC-eNOS) Cell Line was derived from primary mouse aortic...

abm | Caveolin-1 Stable Knockout Mouse Aortic Endothelial (iMAEC-cav1) Cell Line | T3179Immortalization using polyoma middle-sized T-antigen (PmT) methodBiosafety:IIOrganism:MouseSource...

abm | SIRT1 Knockout Stable 293T Cell Line | T3176SIRT1 Knockout Stable 293T Cell Line was established via CRISPR/Cas9 mediated knockout of the endogenously expressing SIRT1 gene also known as...

abm | SIRT1 Knockout Stable DLD-1 Cell Line | T3174SIRT1 Knockout Stable DLD-1 Cell Line was established via CRISPR/Cas9 mediated knockout of the endogenously expressing SIRT1 gene also known as...

abm | SIRT1 Knockout Stable RKO Cell Line | T3172SIRT1 Knockout Stable RKO Cell Line was established via CRISPR/Cas9 mediated knockout of the endogenously expressing SIRT1 gene also known as Sirtuin...

abm | TLR9 Knockout Immortalized Mouse Dendritic Cell Line | T3035As messengers bridging the innate and adaptive immune system, the conventional tissue-resident DC (cDC) acts as sentinels in...

abm | TLR3 Knockout Immortalized Mouse Dendritic Cell Line | T3034As messengers bridging the innate and adaptive immune system, the conventional tissue-resident DC (cDC) acts as sentinels in...

abm | PARP-1 Knockout Immortalized Mouse Heart Endothelial (HYKO6) Cell Line | T3031Poly(ADP-ribose) polymerase 1 (PARP-1) is an ADP-ribosylating enzyme that plays a critical role in DNA damage...

abm | Atg7 Knockout Immortalized Mouse Kidney Epithelial Cell Line | T3028Autophagy is a catabolic process in which proteins and cellular organelles are degraded under metabolic stress through the...

abm | Atg5 Knockout Immortalized Mouse Kidney Epithelial Cell Line | T3027Autophagy is a catabolic process in which proteins and cellular organelles are degraded under metabolic stress through the...

abm | Bax-Bak Double Knockout Immortalized Mouse Kidney Epithelial Cell Line | T3026Key regulators of apoptosis, such as members of the BCL-2 family, have long been linked to the development of...

abm | Bak Knockout Immortalized Mouse Kidney Epithelial Cell Line | T3025Key regulators of apoptosis, such as members of the BCL-2 family, have long been linked to the development of cancer. The Bak...

abm | Bax Knockout Immortalized Mouse Kidney Epithelial Cell Line | T3024Key regulators of apoptosis, such as members of the BCL-2 family, have long been linked to the development of cancer. The Bax...

abm | AT1A-AT1B Double Knockout Immortalized Mouse Renal Proximal Tubule Cell Line | T0628The proximal tubule is part of the nephron duct system in the kidney, involved in regulating the...

abm | AT1B Knockout Immortalized Mouse Renal Proximal Tubule Cell Line | T0627The proximal tubule is part of the nephron duct system in the kidney, involved in regulating the renin-angiotension...

abm | AT1A Knockout Immortalized Mouse Renal Proximal Tubule Cell Line | T0626The proximal tubule is part of the nephron duct system in the kidney, involved in regulating the renin-angiotension...

abm | AT2 Knockout Immortalized Mouse Renal Proximal Tubule Cell Line | T0625The proximal tubule is part of the nephron duct system in the kidney, involved in regulating the renin-angiotension...