Second Messenger Animation 

Epinephrine to cyclic AMP

• PMID: 2841758 DOI: 10.1126/science.2841758

The catecholamines binds to a beta-adrenergic receptor to activate cyclic AMP.

We used the Norepineprhine ELISA from Abbexxa

The beta-adrenergic receptor binds to guanine nucleotide-binding protein (Gs) and adenylate cyclase catalyst (C) till the cAMP-dependent protein kinase is required for heterologous desensitization of adenylyl cyclase.

Animation by Lieven Gevaert, Bio-engineer, RUGent 1996