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HemoVoid™

Hemoglobin Depletion For Erythrocyte Proteomics

  • Hemoglobin voids in flow-through, applicable to red cells, heavily hemolyzed serum, whole blood and dried blood spot (DBS) card
  • Low abundance protein and enzyme enrichment
  • Consumable, cost-effective
  • Mild elution maintains native structure with retained enzymatic, functional and bioactivities
  • Compatible with LC-MS, activity-probe profiling and virtually all proteomic analyses

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HemogloBind™
&
NuGel™ HemogloBind™

Removes Hemoglobin Interference

  • Highly specific for hemoglobin binding
  • depletion from hemolyzed serum, dura, BALF, and whole blood
  • Functional integrity maintained with simple transfer to post-treatment interrogations
  • supports biomarker tests

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HemoVoid™ LC-MS On-Bead

Hemoglobin depletion plus low abundance protein enrichment with optimized on-bead digestion for LC-MS erythrocyte & whole blood proteomics

  • Seamless workflows
  • Unique proteolytic efficiencies
  • Label, label free & phospho- compatible

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HemoVoid™ Blood Card Kit

The HemoVoid™ Blood Card kit substantially reduces hemoglobin interference from dried blood spot protein analytes

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HemogloBind™ Nucleic Acid

Suspension Reagent to remove Hemoglobin interference for PCR

  • Suitable for infectious disease research or rigorous analysis for whole blood or heavily hemolyzed samples
  • Scaleable suspension reagent
  • Robust and simple, no phenol/chloroform or ammonium sulfate precipitation
  • High Yield – free and soluble DNA or RNA is highly recoverable
  • > 95% Hemoglobin and Protein removal from whole blood lysates & dried blood cards
  • Eliminates inhibitory effects of heme for PCR applications
  • Compatible with silica-type final isolation preps

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HemoTrial™ Kit

Includes

  • 5 ml HemogloBind™ +
  • 5 Preps NuGel™ HemogloBind™ +
  • 5 Preps HemoVoid™

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HemogloBind™ Trial Kit

Includes

  • 5 ml HemogloBind™ +
  • 5 Preps NuGel™ HemogloBind™

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HemogloBind™ Blood Card Kit

Hemoglobin Depletion and Protein Enrichment From Dried Blood Spots

  • Dried blood spots are useful for low volume analyses, and simple collection and transport
  • Protocols suitable for inexpensive whole blood card systems, no need for cell separation
  • Hemoglobin binding >90%, with 30-45 minute spin-filter format
  • Protocols based on ≤10 µl whole blood applied, but suspension format is flexible to most volumes
  • Blood proteins and enzymes are enriched for biomarker and proteomic investigations.
  • Removes hemoglobin from diverse species including human, sheep, bovine, goat, rat, mouse, etc.
  • High throughput easicly scalable.

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HemoVoid™ Hemoglobin Variant Enrichment from Blood

Purification & Enrichment Of Hemoglobin From Blood For Hemoglobin Variant Research

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