abm | Huntingtin 150Q Stable PC12 Cell Line | T6018

abm | Huntingtin 150Q Stable PC12 Cell Line | T6018

Huntington disease (HD) is an autosomally dominant degenerative disorder resulting from polyglutamine expansion (>37units) in the huntingtin gene. The repeat is often localized in the N-terminal region of huntingtin and the resulting N-terminal fragments accumulate in the nucleus and become toxic to the cells.

Biosafety:

II

Organism:

Rat

Source Organ:

Adrenal gland

Growth Properties:

Adherent

Morphology:

Small, Irregular

Clones:

N/A

Passage Number:

N/A

Population Doner:

40 - 50 hours

Seeding Density:

30,000 - 50,000 cells/cm²

Markers:

N/A

Applications:

For Research Use Only

Doner Gender:

N/A

Donor Ethnicity:

N/A

Knockdown Method:

N/A

Induction:

N/A

Overexpression:

N/A

Freeze Thaw:

N/A

Propagation:

Cells must be grown in culture vessels coated with Applied Cell Extracellular Matrix

Preservation:

N/A

Quality Control:

N/A

Tumorgenicn:

N/A

Shipping Conditions:

Dry Ice

Storage Contidions:

-180°C