Antiserum to Human IgM (mu chain specific) made in goat | 103002

IgM heavy chain (mu chain) consists of 576 amino acids; there are five mu chains in each IgM molecule. IgM heavy chain is purified by reducing the disulfide bond connecting it to the IgM kappa and lambda light chains. IgM mu chain is more highly conserved across different species than is the heavy chain of IgG or IgA.

Ref: Hayzer, D. J., and Jaton, J-C. 1985. Methods Enzymol. 116, 16; Jeske, D. J., and Capra J. D. 1984. Fundamental Immunology (W.E. Paul, ed.), 131.