InflammaDry® – MMP‑9 Tear Rapid Test

InflammaDry® – MMP-9 Tear Rapid Test

InflammaDry® is a rapid point-of-care test for detecting elevated MMP-9 in human tears, a key biomarker for ocular surface inflammation associated with dry eye disease. It ensures early, accurate diagnosis and better-targeted treatments.

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The Role of InflammaDry® in Detecting MMP-9 Levels for Ocular Surface Inflammation

Inflammation in the ocular surface is a common concern for patients suffering from dry eye disease. One key factor contributing to this inflammation is the presence of Matrix Metalloproteinase-9 (MMP-9), a nonspecific inflammatory marker found in the tears. This article explores the role of InflammaDry®, a clinical immunoassay that detects MMP-9 levels in tears, and its significance in diagnosing dry eye disease and ocular surface inflammation.

Inhibition of matrix metalloproteinase-9 for the treatment of dry eye syndrome - ScienceDirecte

What is MMP-9 and Its Role in Dry Eye Disease ?

MMP-9 (GeneCards) is an enzyme that plays a significant role in tissue remodeling and inflammation. It is released during periods of ocular surface damage and can be detected in the tears of affected individuals. Elevated levels of MMP-9 indicate active inflammation and can serve as an early indicator of dry eye disease, especially in cases where the damage is not yet clinically visible.

A Breakthrough in Detecting Ocular Surface Inflammation

InflammaDry® is a clinically validated, rapid, point‑of‑care immunoassay designed to help eye care professionals detect matrix metalloproteinase‑9 (MMP‑9) in human tears — a key inflammatory biomarker that indicates ocular surface inflammation, often associated with dry eye disease and other ocular surface disorders.

What Makes InflammaDry® Unique ?

First and Only Rapid MMP‑9 Tear Test
InflammaDry® is the first in‑office lateral flow immunoassay that detects elevated MMP‑9 levels — without lab equipment — providing rapid results in about 10 minutes.

Simplicity & Speed
The test uses a disposable cassette and a gentle tear sample from the palpebral conjunctiva. After adding buffer, a reactive strip develops visible lines indicating the presence of elevated MMP‑9, making it ideal for busy clinics.

Clinically Relevant Results
A positive result signals clinically significant inflammation, helping practitioners identify patients who may benefit from anti‑inflammatory therapies, such as topical cyclosporine, lifitegrast, corticosteroids, or other targeted treatments.

Accurate & Practical
With strong sensitivity and specificity reported in studies, InflammaDry® has been shown to support better diagnostic confidence compared to traditional tests alone.