Rabbit SGIP1 Polyclonal Antibody | MBS9203470

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SKU:: MBS9203470
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Availability:: In Stock
Clonality:: Polyclonal
Isotype:: Rabbit Ig
STORAGE OF THE KITS:: Stored at -20°C in shelf life, while up to one month at 4°C.
Host:: Rabbit

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Description

Rabbit SGIP1 Polyclonal Antibody | MBS9203470

Clonality

Polyclonal

Isotype

Rabbit Ig

Host

Rabbit

Species Reactivity

Human, mouse (Predicted Reactivity: Rat)

Specificity

This SGIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SGIP1.

Purity/Purification

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Form/Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis.

Cellular Location

Membrane, clathrin-coated pit; Peripheral membrane protein; Cytoplasmic side

Tissue Location

Specifically expressed in brain.

Preparation and Storage

Maintain refrigerated at 2-8°C for 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

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