VEGF Receptor 2 Rabbit pAb | A11127

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SKU:: A11127
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Availability:: In Stock
Host species:: Rabbit
Purification method:: Affinity purification
Isotype:: IgG
Reactivity:: Human, Mouse, Rat
Storage buffer:: Store at -20℃

€193.70 - €663.00

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VEGF Receptor 2 Rabbit pAb | A11127

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

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