Description
NuGel™ Poly-Epoxy For Immobilization
- Non-specific sites are virtually eliminated by a polymer coating
- Stable across a wide pH range 2 – 10
- Application includes:Immobilization of small ligands containing amino groups for example: hormones, peptides, haptens, drugs etc.
Silica has been an industry standard as an advantageous matrix suitable for high performance liquid chromatography. With NuGel™, non-specific sites have been virtually eliminated making it an ideal support for affinity purification. Through a proprietary polymer coating, Silica is crosslinked forming a reactive Poly-Epoxy functionality stable across a wide pH range (pH 2 to 10). From this foundational chemistry, all of the NuGel™ affinity products are derived.
NuGel™ Poly-Epoxy Technical Data
NuGel™ Poly-Epoxy has a proprietary polymer coating, silica is cross linked forming a reactive Poly-Epoxy functionality stable across a wide pH range (pH 2 to 10). This support contains epoxy groups at the end of hydrophilic spacer arms and is used to couple ligands containing amino groups, thiol groups, proteins and peptides. Compatible with organic solvents.
| Technical Data | |
|---|---|
| Spacer Arm | Polymerized hydrophilic carbon chain |
| Porosity | 1000Å |
| Average Particle Size | 50um |
| Substitution Level | 100-200 uEq/gm of epoxy groups |
Special Features:
- Couples ligands containing free amino or thiol groups at pH 7.5 to 9.0.
- Couples non-polar ligands in organic solvents.
Click Here To View NuGel™ Poly-Epoxy Product Protocol