AffiAB® Goat Anti-Rab8 Polyclonal IgG Antibody

Goat Anti-Mouse Rab8 IgG Polyclonal AntibodyAB3176

Overview: Goat polyclonal antibody to mouse Rab8. Rab8 belongs to the small GTPase superfamily, Rab family. It has cell-type specific function during the process of exocytosis and coordinates regulation of the cytoskeleton. Rab8 also appears to interface with endocytic recycling circuits. At the molecular level, this GTPase regulates both the export of vesicles from the trans-Golgi apparatus, and the directed translocation along actin filaments and microtubules.

Other Names: RAB8A, RAB8B, RAS-associated protein RAB8A, ras-related protein Rab-8B, ras-related protein Rab-8A, ras-related protein Rab-8B antibody.

Other Names: RAB8A, RAB8B, RAS-associated protein RAB8A, ras-related protein Rab-8B, ras-related protein Rab-8A, ras-related protein Rab-8B antibody.

Concentration: 3 mg/ml

Antibody Type: Primary

Target Type: Anti-Rab8

Accession Number: ENSG00000167461

Host Species: Goat

Immunogen Species: Mouse

Immunogen Type: Recombinant protein

Immunogen: Purified recombinant peptide derived from within residues 107 aa to the C-terminus of mouse Rab8a and Rab8b produced in E. coli.

Isotype: IgG

Clonality: Polyclonal

Confirmed Reactive Species: Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other

Specificity Detail: Detects total Rab8 protein in the following human, rat and mouse whole cell lysates and transfected cells with GFP-Rab8a and GFP-Rab8b cds by Western blot.

Buffer: PBS, 20% glycerol and 0.05% sodium azide

Purification: Epitope affinity purified

Conjugation: Unconjugated

Format: N/A

Application: WB, IF, IHC-P, IHC-F

Concentration/Dilution: WB:1:250-1:1,000, IF:1:50-1:250, IHC-P:1:250-1:500, IHC-F:1:250-1:500

Storage:

References: 1. Schiweck J, Murk K, Ledderose J, et al. Nature Communications, 2021. PMID: 33674568, 2. Schiweck J, Murk K, Ledderose J, et al. bioRxiv 2020