Description
Recombinant Human s-COMT V158M, His-tagged | 12 210 002\12 210 003 | BioTeZ
Product Features:
Product Group: Protein
Minimum Shelf life Time in months: 6 months
Package size (cm) in Europe/ ouside Europe: 26 x 17 x 19 \33 x 25 x 23
Application: Recombinant s-COMT V158M is used to study the elimination of biologically active or toxic catechols and some other hydroxylated metabolites. It acts as detoxicating barrier between blood and other tissues. COMT activity may regulated the amounts of dopamine and norepinephrine in various parts of the brain and therefore be associated with mood and other metal processes. The enzyme can also serve as standard in enzymatic and immunochemical assays.
Concentration: 0.5 µg/µl
Buffe: s-COMT V158M is solubilized in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl.
Molecular Weight: 25.5 kDa
Host: N/A
Clonality: N/A
Conjugate: His-tagged
Immunogen Info: N/A
Product description: Recombinant human s-COMT/Natural Variant 108/158 Val->Met (51-271) is produced in E. coli. The protein consists of amino acids M51-P271 of MB-COMT (membrane bound) and a C-terminal His6-tag
Reactivity: N/A
Cross Reactivity: N/A
No Cross Reactivity: N/A
Sequence: MGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGMKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKAIYKGPGSEAGPHHHHHH
Addtional Names: soluble Catechol-O-Methyltransferase
Specificity: N/A
Format: liquid
Purity: > 95%
Purification: N/A
Storage: Store at -70°C
Shipping Temp Min: dry ice
Isotype: N/A
Clone: N/A
Source: Recombinant, E.coli
Gene ID: N/A
Uniprot/NCBI/GeneID: P21964-2
NCBI Official Symbol: N/A
NCBI Official Full Name: Catechol-O-Methyltransferase
NCBI Organism: Homo sapiens