Anti-PON1 Clone KRJ2

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PON1 is a polymorphic enzyme closely associated with high-density lipoproteins. It is located on chromosome 7 along with 2 other paraoxanase genes, PON2 and PON3. It is a 355 amino acid, 43 kDa glycoprotein produced in the liver and secreted into the bloodstream. Gene polymorphisms occur in both coding and non-coding regions. Two major polymorphisms in the coding region are L55M and Q192R. Q192R polymorphisms result in three major functional phenotypes Q/Q, Q/R and RR. PON1 hydrolyses organophosphates and prevents the oxidation of low-density lipoproteins. It may inhibit the progression of atherosclerosis by inhibition of LDL oxidation. Levels of PON1 in serum vary among individuals and are decreased in chronic renal failure, liver cirrhosis, diabetes, peripheral neuropathy, and familial hypercholesterolemia.

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4 Reviews

  • 4


    Posted by Camila on 22nd Jun 2022

    todo el trabajo de Genatur desde el empaque hasta la entrega es simplemente sobresaliente. El personal calificado y talentoso nunca da la oportunidad de quejarse.

  • 5

    Consegna veloce

    Posted by Alice on 22nd Jun 2022

    Inaspettatamente la consegna è stata velocissima. Servizio molto efficiente in poco tempo

  • 5

    superior quality

    Posted by Carson on 22nd Jun 2022

    The quality highly superior qulaity products never found any fault in their products. Really Awesome!

  • 5

    its perfect

    Posted by Jase on 4th Dec 2021

    I just received this product today. It is easy to use.

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