WWOX Polyclonal Antibody | BS-0589R

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SKU:: BS-0589R
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Availability:: In Stock
Size:: 100 ul
oncentration:: 1ug/ul
Cross Reactive Species:: Human Mouse

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Description

WWOX Polyclonal Antibody | BS-0589R

Host: Rabbit

Target Protein: WWOX

Immunogen Range: 5-100/414

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 51741

Swiss Prot: Q9NZC7

Source: KLH conjugated synthetic peptide derived from human WWOX

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.

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