WWOX Polyclonal Antibody | BS-0589R
- SKU:
- BS-0589R
- Availability:
- In Stock
- Size:
- 100 ul
- oncentration:
- 1ug/ul
- Cross Reactive Species:
- Human Mouse
Description
WWOX Polyclonal Antibody | BS-0589R
Host: Rabbit
Target Protein: WWOX
Immunogen Range: 5-100/414
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 51741
Swiss Prot: Q9NZC7
Source: KLH conjugated synthetic peptide derived from human WWOX
Purification: Purified by Protein A.
Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.
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