Ferritin ELISA CE | CTK-E5010

The CTK Ferritin ELISA is a solid-phase enzyme-linked immunosorbent assay. The five components are:

• Solid microwells pre-coated with streptavidin

• FTN Calibrators

• FTN Assay Control

• FTN Biotin Reagent comprised of anti-FTN conjugated to biotin (Bio-Ab) and

• FTN Enzyme Reagent comprised of anti-FTN conjugated to HRP enzyme (HRP-Ab) This test is intended for the quantitative determination of ferritin (FTN) concentration in human serum. It is intended to be used by professionals as an aid in the measurement of iron status. Any interpretation or use of this test result must also rely on other clinical findings as well as on the professional judgment of health care providers. Recommended for use:

• Aid in measurement of iron status in human serum from individual subjects

• Monitor iron levels, especially if a patient has iron-related conditions such as anemia, hemochromatosis, porphyria, chronic inflammatory disorder, liver disease, hyperthyroidism, Leukemia, Hodgkin’s lymphoma, or alcohol abuse. Ferritin is a 24-subunit, intracellular protein core that functions to store and release iron. Under normal circumstances, serum ferritin concentration is positively correlated with the total amount of iron stored in the body. Low concentration of serum ferritin usually indicates iron deficiency. Iron deficiency is one of the major causes of anemia which is most prevalent in highly susceptible populations, which include pregnant women and children. If serum ferritin concentration is high, it may indicate iron overload, and may be the result of high body mass index, aging, or the presence of inflammation, infection, or liver or kidney disease. Measurement of iron status by serum ferritin is important for accurate classification of iron status in individuals, in order to provide treatment for iron deficiency or plan of care for elevated serum ferritin concentration.