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Parvovirus B19 RT-PCR Quant (CE) | V49-FRT

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SKU:
441-V49-FRT
Availability:
Delivery On Request
Test Size:
55
£740.00 - £1,522.00

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Description

Parvovirus B19 RT-PCR Quant (CE) | V49-FRT from Sacace Biotechnologies is available for delivery

Real Time PCR Kit for quantitative detection of Parvovirus B19

Storage & Shipping :

The kit can be shipped at 2-8°C for 3-4 days but should be stored at 2-8°C and -20°C immediately on receipt.

Parvovirus B19 RT-PCR Quant (CE) V49-FRT DataSheet

INTRODUCTION

Human Parvovirus B19 was first identified in 1975. B19 is widespread, and manifestations of infection vary with the immunologic and hematologic status of the host. In healthy immunocompetent individuals B19 is the cause of erythema infectiosum and, particularly in adults, acute symmetric polyarthropathy. Due to the tropism of B19 to erythroid progenitor cells, infection in individuals with an underlying hemolytic disorder causes transient aplastic crisis. In the immunocompromised host persistent B19 infection is manifested as pure red cell aplasia and chronic anemia. Likewise, the immature immune response of the fetus may render it susceptible to infection, leading to fetal death in utero, hydrops fetalis, or development of congenital anemia.

Diagnosis is primarily based on detection of specific antibodies by enzyme-linked immunosorbent assay or detection of viral DNA by PCR. Viremia in persistent and recurrent infection may range from very low to high titers and may be associated with chronic clinical manifestations, such as chronic anemia. Quantitative B19-DNA PCR assay can help guide the choice of treatment in persistent infections (i.e., intravenous immunoglobulin (IVIG) treatment vs immunosuppression reduction).

The high levels of sensitivity, specificity, and rapidity provided by the PCR technology for the detection and quantitation of B19 DNA represent a significant improvement for the laboratory diagnosis of B19 infection.

INTENDED USE

The Parvovirus B19 Real-TM is a Real-Time test for the quantitative detection of Parvovirus B19 in the biological materials. DNA is extracted from samples, amplified using real time amplification with fluorescent reporter dye probes specific for Parvovirus B19 and Internal Control (IC). Test contains an IC which serves as an amplification control for each individually processed specimen and to identify possible reaction inhibition.

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1 Review

  • 5
    outstanding

    Posted by Antonio on 7th Jan 2022

    their , response, shipping and the way they deliver their products safely is outstanding

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