Prominin 1 (PROM1) Antibody | abx019041
- SKU:
- abx019041
- Availability:
- Shipped within 5-10 working days.
- Clonality:
- Polyclonal
- Tested Applications:
- WB, IHC-P, IF/ICC
- Host:
- Rabbit
- Conjugation:
- Unconjugated
- Dry Ice:
- No
Description
Prominin 1 (PROM1) Antibody. Cat# abx019041. Supplier: abbexa.
CD133 Antibody is a rabbit polyclonal antibody against human, mouse and rat CD133 (prominin-1). In humans, the CD133 glycoprotein is encoded by the PROM1 gene and is approximately 100-120 kDa in weight. This protein is a member of the pentaspan transmembrane glycoprotein (5-TM) family, which specifically localize to cellular protrusions. CD133 is expressed in a broad range of cell types including haematopoietic stem cells, mammary glands and cells of the digestive tract. Its expression is regulated by several different factors including TGF beta 1 and microRNA.
CD133 has also been identified as a key modulator of several different functions in cancer cells including tumorigenesis and metastasis which promotes their growth, spread and survival. As a result, CD133 is now frequently used as a biomarker for detecting and isolation stem cell and cancer cell populations. Abbexa's CD133 Antibody (abx019041) has been tested in several different applications including Western blotting (WB), immunohistochemistry, immunofluorescence (IF/ICC) and flow cytometry. This allows for the detection, observation and isolation of CD133 and CD133+ cells.
| Target | Prominin 1 (PROM1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC-P, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/250 - 1/500, IHC-P: 1/50, FCM: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant human CD133. |
| Isotype | IgG |
| Purification | Immunogen affinity purified. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O43490 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6SV49, Q6SV50, Q6SV51, Q6SV52, Q6SV53, Q96EN6 |
| UniProt Entry Name | PROM1_HUMAN |
| Gene Symbol | PROM1 |
| GeneID | 8842 |
| OMIM | 604365 |
| HGNC | 9454 |
| KEGG | hsa:8842 |
| Ensembl | ENSG00000007062 |
| String | 9606.ENSP00000426809 |
| Buffer | TBS, pH 7.4, 0.5% BSA, 40% glycerol and 0.05% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
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