MOUSE ANTI-LEGIONELLA PNEUMOPHILA ANTIBODY (LN14)

Legionella pneumophila antibody is mouse monoclonal antibody that is specific for Legionella detection.

PRODUCT DETAILS – MOUSE ANTI-LEGIONELLA PNEUMOPHILA ANTIBODY (LN14)

• Mouse anti-Legionella pneumophila monoclonal IgG3 antibody (clone LN14).
• Greater than 95% purity by SDS-PAGE and buffered in PBS, pH7.4.

BACKGROUND

Legionella pneumophila is a gram-negative, non-encapsulated bacterium of the genus Legionella, a member of the family Legionellaceae. In nature, L. pneumophila naturally exists in fresh water environments and infects protozoa, which are natural hosts for L. pneumophila. However, the development and increased use man made water systems such as air-conditioning systems, fountains, hot tubs and showers has enabled L. pneumophila to successfully thrive and infect susceptible humans through water droplets produced by these systems.

L. pneumophila is an opportunistic intracellular pathogen that was first recognised in a group of individuals, presenting with a lung infection, who had attended a convention in Philadelphia in 1976. It is the causative agent of a severe type of pneumonia referred to as Legionnaires’ disease. The symptoms of Legionnaires’ disease include shortness of breath, cough, headache, fever and muscle ache, which can occur 2 – 10 days after exposure. Complications associated with infection may result in death. L. pneumophila may also cause a mild form of disease known as Pontiac fever, which is self-limiting and doesn’t require hospitalisation (CDC). Both forms of the disease may also be referred to as Legionellosis.

REFERENCES

• Centers for Disease Control and Prevention: Legionella (Legionnaires’ disease and Pontiac fever).