Human C-Reactive Protein (CRP) | ABMC-P10
- SKU:
- ABMC-P10
- Availability:
- Usually shipped in 5 working days
Description
Human C-Reactive Protein (CRP) | ABMC-P10
| Concentration: | 1 mg / ml, determined by the Lowry method |
| Source: | From human pleural fluid. |
| Purity: | ≥ 99% by SDS-PAGE |
| Buffer: | 50 mM Tris-HCl, 250 mM NaCl, 5 mM CaCl2, 0.1% NaN3, pH 8.0. |
| Storage: | -20°C for long-term storage, 4°C for short- term storage. Aliquot to avoid repeated freezing and thawing. |
*The products are for research or manufacturing use only, not for use in human therapeutic or diagnostic applications.
IMPORTANCE
Human C-Reactive Protein (CRP) is an important biomarker for predicting of future cardiovascular events, such as heart attack and stroke (Koenig et al., 1999, Jenny et al., 2007, Kabagambe et al. 2011). CRP is an acute phase protein produced by the liver. It is a member of the pentraxin family of proteins with five identical nonglycosylated subunits of 206 amino acids each (m.w. 23 kDa) (Agrawal et al., 2009).
Among other markers of inflammation, CRP has shown the strongest association with cardiovascular events (Marsik et al., 2008, Kones et al., 2010). Clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. It is an important biomarker for detecting individuals at high risk of plaque rapture.
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