ATTO Luminometer

The Luminometer category encompasses advanced instruments designed for the detection and quantification of luminescence emitted during various biochemical reactions. These systems are integral to molecular biology, pharmacology, and clinical diagnostics, facilitating sensitive and high-throughput analysis of luminescent signals.

Key Technical Features

• High-Sensitivity Detection
  Equipped with photomultiplier tubes (PMTs) and advanced photon counting systems, these luminometers achieve detection limits as low as 1 zeptomole (10⁻²¹ moles) of luciferase molecules, ensuring precise measurement of low-intensity luminescent signals. 
• Wide Spectral Range
  Capable of detecting luminescence across a broad wavelength spectrum (350–670 nm), accommodating various assays and reporter systems. 
• Temperature Control
  Integrated incubation systems maintain optimal conditions (ambient +5°C to 40°C) for live-cell assays, preserving cell viability during prolonged measurements.
• Automated Reagent Injection
  Built-in auto-injection systems enable precise and reproducible reagent delivery, enhancing assay consistency and throughput.
• Multi-Color Detection
  Advanced optical filtering systems allow simultaneous detection of multiple luminescent signals, facilitating complex assays involving multiple reporters. 

Applications

• Gene Expression Analysis
  Quantification of transcriptional activity using single, dual, or triple reporter assays to study gene regulation mechanisms.
• ATP Assays
  Measurement of cellular ATP levels as indicators of cell viability, proliferation, and cytotoxicity.
• Immunoassays
  High-sensitivity detection of antigens or antibodies in various sample types, aiding in diagnostics and research. 
• Autophagy and Oxidative Stress Studies
  Monitoring of autophagic activity and antioxidant responses in cells under different experimental conditions. 
• Live-Cell Imaging
  Real-time monitoring of bioluminescence in living cells and tissues, enabling dynamic studies of cellular processes.