hTERT Cell Immortalization Kit | 568-hTERT

(No reviews yet) Write a Review
SKU:
568-hTERT
Availability:
5 to 7 Days Shipment
Size:
5 x 20 ul
£3,321.03

 Select your currency from the header

Description

hTERT Cell Immortalization Kit | 568-hTERT from 101Bio Supplied by Gentaur Genprice.

Product Overview: It is well known that primary cells only undergo a pre-determined and finite number of cell divisions in culture. After limited population doublings (the number of which varies by species, cell type, and culture conditions), primary cells enter a state, so-called replicative senescence, where they can no longer divide. To surpass senescence, several methods exist for immortalizing mammalian cells in culture. The most recently discovered approach to cell immortalization is through the expression of Telomerase Reverse Transcriptase protein (TERT) . It is particularly useful for cells that are most affected by telomere length, including many human cell types. This protein is usually silenced in most somatic cells. These cells can avoid replicative senescence by maintaining sufficient telomere lengths when hTERT is exogenously introduced. However, over-expression of hTERT in some cell types (especially in epithelial cells) fails to induce cell immortalization.

Shipping/Storage Temperature: Store -80℃, ship in Dry Ice

Shelf Life: 6 months

View AllClose

0 Reviews

View AllClose