Stat1 (phospho Tyr701) Polyclonal Antibody | ABP50405

Product Overwiew:

Rabbit Anti-Stat1 (phospho Tyr701) Polyclonal Antibody

Background:

Signal transducer and activator of transcription 1 encoded by STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. Signal transducer and activator of transcription 1can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. Signal transducer and activator of transcription 1 mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Phospho-Stat1 (Y701) Polyclonal Antibody detects endogenous levels of Stat1 protein only when phosphorylated at Y701.

Host:

Rabbit

Sequence:

N/A

Reactivity:

Human, Mouse, Rat, Monkey

Application:

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IP (2-5 ug/mg lysate), ELISA (1:10000). Not yet tested in other applications.

Used for:

IF, WB, IHC-P, IP, ELISA

Kit components:

N/A

Features & Benefits:

N/A

Usage Notes:

N/A

Storage buffer:

PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.

Storage instructions:

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Shipping:

Gel pack with blue ice.

Precaution:

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.