Cell Senescence Kit (β-Galactosidase Assay) | KTA3010

Product Overwiew:

Abbkine Cell Senescence Kit (β-Galactosidase Assay) provides reagents for detecting the senescent cells or tissues.

Background:

Cellular senescence is a phenomenon in which normal cells cease to divide. The senescent cells can no longer replicate, but they still maintain metabolically active and stain positive for senescence-associated beta-galactosidase activity, which is considered to be a biomarker of cellular senescence. Cellular senescence can be achieved by the activation of oncogenes and cell-cell fusion, DNA damage in response to elevated reactive oxygen species (ROS), rather than relying solely on the number of cellular divisions. During normal aging, the number of senescent cells in tissues increases significantly.

Used for:

N/A

Kit components:

• X-gal (lyophilized)
• Fixation Buffer (10×)
• Reagent A
• Reagent B
• Reagent C

Features & Benefits:

• Optimized assay protocol, suitable for cellular senescence detection of senescent cells or tissues.
• Only stain senescent cells and does not stain presencent cells, quiescent cells, immortal cells or tumor cells.

Usage Notes:

The β-galactosidase staining solution is toxic and corrosive to the human body. Please be careful when handling it, and pay attention to effective protection. Avoid contacting with the human body or inhalation directly.

Storage buffer:

N/A

Storage instructions:

Stable for at least 12 months at -20°C from date of shipment.

Shipping:

Gel pack with blue ice.

Precaution:

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.