Calcein AM | BMD00064

Product Overwiew:

Calcein AM is a cell-permeable dye.

Background:

Calcein AM is a cell-permeable dye that, upon entering live cells, is cleaved by intracellular esterases, leaving membrane-impermeant calcein, a fluorescent indicator with absorption and emission maxima of 494 and 517 nm, respectively. It can be used as an indicator of cell viability, cell-cell communication, cytotoxicity, or changes in intracellular calcium, fluoride, iron, or mercury. As calcein is a substrate for multidrug resistance-associated protein 1 (MRP1) and multidrug resistance protein 3 (MDR3, P-glycoprotein 3), calcein AM is used to study these proteins and their regulation.

Used for:

N/A

Kit components:

N/A

Features & Benefits:

• λEX/λEm: 494/517 nm (pH 8) (calcein)

Usage Notes:

• Soluble in DMSO

Storage buffer:

N/A

Storage instructions:

Store at -20°C. The product can be stored for up to 12 months. Protect from light.

Shipping:

Gel pack with blue ice.

Precaution:

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.