Human IL-1 beta protein | PRP1019

Product Overwiew:

Recombinant Human IL-1 beta protein expressed in E. coli.

Background:

Interleukin-1 beta (IL-1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL-1 beta is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). IL-1 beta is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by Interleukin 1β in the central nervous system (CNS). IL-1 beta gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Host:

N/A

Sequence:

Amino acid sequence derived from human IL-1 beta (NP_000567.1) (Ala 117-Ser 269) was expressed.

Reactivity:

N/A

Application:

N/A

Used for:

N/A

Kit components:

N/A

Features & Benefits:

Endotoxin: < 0.01 EU per μg of the protein as determined by the LAL method.

Usage Notes:

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human GM-CSF protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

Storage buffer:

N/A

Storage instructions:

Lyophilized Human IL-1 beta protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Shipping:

The product is shipped at ambient temperature.

Precaution:

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.