Mouse TNF-alpha protein | PRP1113

Product Overwiew:

Recombinant Mouse TNF-alpha protein expressed in E. coli.

Background:

Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is a pleiotropic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-α is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-α also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes.

Host:

N/A

Sequence:

Amino acid sequence derived from Mouse TNF-alpha isoform (P06804) (Leu80-Leu235) was expressed.

Reactivity:

N/A

Application:

N/A

Used for:

N/A

Kit components:

N/A

Features & Benefits:

Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.

Usage Notes:

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Mouse TNF-alpha protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

Storage buffer:

N/A

Storage instructions:

Lyophilized Mouse TNF-alpha protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Shipping:

The product is shipped at ambient temperature.

Precaution:

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.