abm | AZ-GR Stable HeLa Luciferase Reporter Cell Line | T3103

abm | AZ-GR Stable HeLa Luciferase Reporter Cell Line | T3103

The glucocorticoid receptpr (GR) is a ligand-activated transcription factor that binds endogenous glucocorticoids such as cortisol and synthetic glucocorticoids commonly used as anti-inflammatory or immunosuppressive drugs. The AZ-GR Stable HeLa Luciferase Reporter Cell Line is a selective, sensitive and reliable tool for high throughput gene reporter assays examining GR activity. It was created by stably transfecting plasmids containing glucocorticoid response elements (GREs) coupled with the luciferase reporter gene in to HeLa cells with endogenous GR. This cell line is particularly efficient for research on pre-clinical studies investigating novel glucocorticoid pharmaceuticals or for environmental applications, such as monitoring the levels of steroid hormones present in soil or water samples.

Biosafety:

II

Organism:

Human

Source Organ:

Cervix

Growth Properties:

Adherent

Morphology:

Epithelial-like

Clones:

N/A

Passage Number:

N/A

Population Doner:

N/A

Seeding Density:

Thaw entire contents into an appropriate T25 flask as specified in the Propagation instructions.

Markers:

N/A

Applications:

For Research Use Only

Doner Gender:

Female

Donor Ethnicity:

N/A

Knockdown Method:

N/A

Induction:

N/A

Overexpression:

N/A

Freeze Thaw:

N/A

Propagation:

The base medium for this cell line is Prigrow III medium available at abm

Preservation:

N/A

Quality Control:

Selective growth on media containing hygromycin B (0.2 mg/ml)

Tumorgenicn:

N/A

Shipping Conditions:

Dry Ice

Storage Contidions:

-180°C