abm | PDPN CRISPR Stable Knockout COS-7 Cell Line | T6039

abm | PDPN CRISPR Stable Knockout COS-7 Cell Line | T6039

Podoplanin (PDPN), also known as Aggrus, possesses three tandem repeat of platelet aggregation-stimulating (PLAG) domains in its N-terminus. The COS-7 Cell Line which is derived from African Green Monkey kidney tissue was transfected with CRISPR/Cas9 plasmids that target PDPN to generate the PDPN CRISPR Knock Out COS-7 Cell Line (African Green Monkey). This cell line could be used to further study the PDPN gene and its applications with cancer metastasis. This cell line is also useful in testing anti-hPDPN monoclonal antibodies.

Biosafety:

II

Organism:

Cercopithecus aethiops (African Green Monkey)

Source Organ:

Kidney

Growth Properties:

Adherent

Morphology:

Polygonal

Clones:

N/A

Passage Number:

N/A

Population Doner:

N/A

Seeding Density:

N/A

Markers:

N/A

Applications:

For Research Use Only

Doner Gender:

N/A

Donor Ethnicity:

N/A

Knockdown Method:

Transfection using CRISPR/Cas9 plasmid that target PDPN

Induction:

N/A

Overexpression:

N/A

Freeze Thaw:

N/A

Propagation:

The base medium for this cell line is Prigrow III medium available at abm

Preservation:

1. Freeze Medium: Complete growth medium with 20% FBS and 10% DMSO. 2. Storage Temperature: Liquid nitrogen vapour phase.

Quality Control:

N/A

Tumorgenicn:

N/A

Shipping Conditions:

Dry Ice

Storage Contidions:

-180°C