abm | Prothrombin Mutant (R393Q) Stable Expressing HEK293 Cell Line | T6353

abm | Prothrombin Mutant (R393Q) Stable Expressing HEK293 Cell Line | T6353

Mannan-binding lectin-associated serine protease-1 (MASP-1) is a protein of the lectin pathway. Its similar in terms of structural features and substrate specificity to thrombin. Via its ability to induce fibrin clot formation along with interplay with several coagulation factors, MASP-1 has been shown to activate prothrombin. With the Prothrombin Mutant (R393Q) Stable Expressing HEK293 Cell Line, you can investigate in detail the mechanism of MASP-1 in mediating prothrombin activation.

Biosafety:

II

Organism:

Human

Source Organ:

Kidney

Growth Properties:

Adherent

Morphology:

Epithelial

Clones:

N/A

Passage Number:

N/A

Population Doner:

N/A

Seeding Density:

N/A

Markers:

Prothrombin mutant (R393Q)

Applications:

For Research Use Only

Doner Gender:

N/A

Donor Ethnicity:

N/A

Knockdown Method:

N/A

Induction:

N/A

Overexpression:

N/A

Freeze Thaw:

N/A

Propagation:

The base medium for this cell line is Prigrow III medium available at abm

Preservation:

1. Freeze Medium: Complete growth medium with 10% FBS and 5% DMSO.
2. Storage Temperature: Liquid nitrogen vapour phase.

Quality Control:

1) ELISA; 2) Western blot; 3) Kinetic analysis

Tumorgenicn:

N/A

Shipping Conditions:

Dry Ice

Storage Contidions:

-180°C