abm | Stable CHO-K1 Expressing GADD34 Q525X Mutant (CHO-K1-G34M) Cell Line | T6980

abm | Stable CHO-K1 Expressing GADD34 Q525X Mutant (CHO-K1-G34M) Cell Line | T6980

The Stable CHO-K1 Expressing GADD34 Q525X Mutant (CHO-K1-G34M) Cell Line carries a nonsense mutation, termed Q525X mutation in the GADD34 gene. The nonsense mutation at Gln525 from CAG in wildtype to TAG in the mutant at his residue produces a premature termination codon. These cells have higher levels of eIF2α phosphorylation compared to the control CHO-K1-normal cells both in the presence and absence of endoplasmic reticulum stress. The Stable CHO-K1 Expressing GADD34 Q525X Mutant (CHO-K1-G34M) Cell Line is an essential model for studies focusing on GADD34 gene.

Biosafety:

II

Organism:

Chinese hamster

Source Organ:

Ovary

Growth Properties:

Adherent

Morphology:

Polygonal

Clones:

N/A

Passage Number:

N/A

Population Doner:

25 - 35 hours

Seeding Density:

15,000 - 20,000 cells/cm²

Markers:

N/A

Applications:

For Research Use Only

Doner Gender:

N/A

Donor Ethnicity:

N/A

Knockdown Method:

N/A

Induction:

N/A

Overexpression:

N/A

Freeze Thaw:

N/A

Propagation:

The base medium for this cell line is Prigrow X medium available at abm

Preservation:

1. Freeze Medium: Complete growth medium with 20% FBS and 10% DMSO. 2. Storage Temperature: Liquid nitrogen vapour phase.

Quality Control:

N/A

Tumorgenicn:

N/A

Shipping Conditions:

Dry Ice

Storage Contidions:

-180°C