Description
Goat Anti-Human CD4 IgG Polyclonal AntibodyAB0091
Overview: Goat polyclonal antibody to CD4. CD4 is a member of the immunoglobulin superfamily, a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and a receptor for the human immunodeficiency virus. This protein is expressed not only on the surface of T helper cells and regulatory T cells but also on monocytes, macrophages and dendritic cells. It functions to initiate or amplify the early phase of T-cell activation and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system.
Other Names: CD4mut, CD4 antigen (p55), CD4 Receptor, T-cell surface antigen T4/Leu-3 and T-cell surface glycoprotein CD4 antibody.
Other Names: CD4mut, CD4 antigen (p55), CD4 Receptor, T-cell surface antigen T4/Leu-3 and T-cell surface glycoprotein CD4 antibody.
Concentration: 3 mg/ml
Antibody Type: Primary
Target Type: Anti-CD4
Accession Number: ENSG00000010610
Host Species: Goat
Immunogen Species: Human
Immunogen Type: Recombinant protein
Immunogen: Purified recombinant peptide derived from within 50 to 235 aa, corresponding to the external domain of human CD4 produced in E. coli.
Isotype: IgG
Clonality: Polyclonal
Confirmed Reactive Species: Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other
Specificity Detail: Using spleen lysate detects a 52 kDa band by Western blot.
Buffer: PBS, 20% glycerol and 0.05% sodium azide
Purification: Epitope affinity purified
Conjugation: Unconjugated
Format: N/A
Application: WB
Concentration/Dilution: WB:1:500-1:2,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000
Storage:
References: 1. Helsby MA, Leader PM, Fenn JR, et al. BMC Cell Biol. 2014 Feb. PMID:24528853