AffiAB® Goat Anti-CD4 Polyclonal IgG Antibody

Goat Anti-Human CD4 IgG Polyclonal AntibodyAB0091

Overview: Goat polyclonal antibody to CD4. CD4 is a member of the immunoglobulin superfamily, a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and a receptor for the human immunodeficiency virus. This protein is expressed not only on the surface of T helper cells and regulatory T cells but also on monocytes, macrophages and dendritic cells. It functions to initiate or amplify the early phase of T-cell activation and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system.

Other Names: CD4mut, CD4 antigen (p55), CD4 Receptor, T-cell surface antigen T4/Leu-3 and T-cell surface glycoprotein CD4 antibody.

Other Names: CD4mut, CD4 antigen (p55), CD4 Receptor, T-cell surface antigen T4/Leu-3 and T-cell surface glycoprotein CD4 antibody.

Concentration: 3 mg/ml

Antibody Type: Primary

Target Type: Anti-CD4

Accession Number: ENSG00000010610

Host Species: Goat

Immunogen Species: Human

Immunogen Type: Recombinant protein

Immunogen: Purified recombinant peptide derived from within 50 to 235 aa, corresponding to the external domain of human CD4 produced in E. coli.

Isotype: IgG

Clonality: Polyclonal

Confirmed Reactive Species: Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other

Specificity Detail: Using spleen lysate detects a 52 kDa band by Western blot.

Buffer: PBS, 20% glycerol and 0.05% sodium azide

Purification: Epitope affinity purified

Conjugation: Unconjugated

Format: N/A

Application: WB

Concentration/Dilution: WB:1:500-1:2,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000

Storage:

References: 1. Helsby MA, Leader PM, Fenn JR, et al. BMC Cell Biol. 2014 Feb. PMID:24528853