Transthyretin (Wild Type) Human, Recombinant | T-500-10

Transthyretin (Wild Type) (1.0mg) Human, Recombinant | T-500-10 | AlexoTech

Transthyretin (TTR), formerly known as Prealbumin, is in vivo involved in the binding and transportation of the Thyroxin hormone and retinol-binding protein. Mutations in TTR are associated with familial amyloidotic polyneuropathy (FAP) which is a fatal disease characterized by amyloid depositions found in visceral organs including the heart, liver, and kidney. The wild type form of TTR is associated with a late onset amyloidosis denoted senile systemic amyloidosis, affecting around 25% of the population above 80 years of age with depositions mainly found in the heart.