MOUSE ANTI-CAMPYLOBACTER JEJUNI ANTIBODY (CA30)

Campylobacter jejuni antibody (clone CA30), is a mouse monoclonal antibody that is specific for the detection of Campylobacter jejuni. The antibody does not cross react with Helicobacter pylori, Escherichia coli, Salmonella enteriditis, Salmonella paratyphi, Salmonella typhi, Salmonella typhimurium, Shigella boydii, Shigella dysenteriae, Shigella flexneri, Shigella sonnei, Yersinia enterocolitica, Listeria monocytogenes, Staphylococcus aureus.

PRODUCT DETAILS – MOUSE ANTI-CAMPYLOBACTER JEJUNI ANTIBODY (CA30)

• Mouse anti Campylobacter jejuni monoclonal antibody (clone CA30).
• Isotype – Mouse IgG1.
• Greater than 95% purity by SDS-PAGE.
• Suitable for ELISA and Western blotting.

BACKGROUND

The bacterial genus Campylobacter are non-spore forming, rod shaped or curved, gram-negative bacteria of the family Campylobacteriacae. Over twenty-five species of Campylobacter have been identified but approximately 90% of human disease is caused by Campylobacter jejuni (C. jeuni). Infectious disease caused by pathogenic Campylobacter species (Campylobacter spp) is referred to as Campylobacteriosis. Other species of Campylobacter causing Campylobacteriosis include C. coli, C.lari and C. upsaliensis but cases are less frequently reported.

Birds, including poultry, are major reservoirs of C. jejuni, where it survives in the intestines and crop of healthy birds. Most reported outbreaks of Campylobacteriosis have been associated with the consumption of undercooked poultry and poultry products. However, transmission of Campylobacter jejuni can also occur via consumption of undercooked meat, unpasteurised milk, contact with animals or, in rare cases, person-to-person contact.

Campylobacteriosis can affect all age groups but commonly affects young children, males and the elderly. Symptoms of infection generally include fever, abdominal cramps, watery or haemorrhagic diarrhoea and weight loss. Symptoms can be more severe and of longer duration in young children and the elderly. Although the disease is self-limiting, complications may develop in some cases after infection, which include irritable bowel syndrome, Guillain Barre syndrome and other autoimmune neuropathies (CDC).

REFERENCES

• Centers for Disease Control and prevention: Campylobacter (Campylobacteriosis)