Rabbit Anti-CBL (Carbamyl-lysine) Affinity Pure, 30% glycerol | ABMC-A27
- SKU:
- ABMC-A27
- Availability:
- Usually shipped in 5 working days
Description
Rabbit Anti-CBL (Carbamyl-lysine) Affinity Pure, 30% glycerol | ABMC-A27
| Host Species: | Goat |
| Concentration: | 1 mg/ml (OD 1.35 / 280 nm) |
| Antigen: | CBL-KLH |
| Purification: | Affinity purified |
| Buffer: | 75 mM Sodium Phosphate, 75 mM NaCl, 0.5 mM EDTA, 0.02% NaN3, pH 7.2, 30% glycerol. |
| Specificity |
Specifically binds to CBL. Dilution for immunoblot and ELISA range: 1,000 to 8,000. (A slight amount of precipitation may have occurred during storage due to the natural properties of these antibodies; please centrifuge before use.). |
| Use: |
The antibody can be used for detection of Carbamylation in plasma, lipoproteins, and other CBL containing proteins, using for immunoassays, immunoblots, enzyme conjugation, or biotinylation. |
| Storage: | -20°C for long-term storage, 4°C for short- term storage. Aliquot to avoid repeated freezing and thawing. |
*These products are for research or manufacturing use only, not for use in human therapeutic or diagnostic applications.
IMPORTANCE
Carbamylation is a spontaneous nonenzymatic modification of proteins and amino acids by urea-derived isocyanate, which is generally present in human serum and is increased in uremic patients (Kraus and Kraus, 2001).
Proteins carbamylated at lysine or the terminal protein amino acids may play an important role in Chronic renal failure subjects in the development of atherosclerosis and cardiovascular diseases (Raine et al., 1991; Culleton et al., 1999).
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