Description
Rabbit Anti-Human Apolipoprotein CII Neat Antiserum | ABMC-S12
Host Species: | Rabbit |
Antigen: | Human Apolipoprotein CII |
Specificity |
Specifically binds to human apo CII. Dilution for immunoblot and ELISA range: 1,000 to 160,000. |
Use: | The antibody can be used for detection of apo CII in plasma and lipoproteins, immunoassays, immunoblots, enzyme conjugation, or biotinylation. |
Storage: | -20°C for long-term storage, 4°C for short- term storage. Aliquot to avoid repeated freezing and thawing. |
IMPORTANCE
Apo CII contains 78 amino acid residues. The m.w. is 8.5 kDa (Jackson et al., 1977).
The lipid-binding domain of Apo CII is localized to a region in the N-terminal with a strongly amphipathic nature (Macphee et al., 1999). Apo CII is also one of the key components of the metabolism of total triacylglycerol-rich lipoproteins by activating lipoprotein lipase that hydrolyzes fatty acids from triacylglycerols in chylomicrons (Kei et al., 2012).