Sheep Anti-Human Apolipoprotein AII Neat Antiserum | ABMC-S05
- SKU:
- ABMC-S05
- Availability:
- Usually shipped in 5 working days
Description
Sheep Anti-Human Apolipoprotein AII Neat Antiserum | ABMC-S05
| Host Species: | Sheep |
| Antigen: | Human Apolipoprotein AII |
| Specificity |
Specifically binds to human apo AII. Dilution for immunoblot and ELISA range: 1,000 to 320,000. |
| Use: |
The antibody can be used for detection of human apo AII in human plasma and lipoproteins, using immunoassays or immunoblots. |
| Storage: | -20°C for long-term storage, 4°C for short- term storage. Aliquot to avoid repeated freezing and thawing. |
IMPORTANCE
Apo AII comprises 25% of HDL. It exists in human plasma as a dimer of 2 identical chains of 77 amino acid residues, joined by disulfide. The molecular weight is reported to be 8.7 kDa for a single chain (Brewer et al., 1972).
Studies on mouse reported that apo AII may be proatherogenic (Warden et al., 1993); however, case-control study in the large European Prospective Investigation demonstrated that plasma Apo AII concentrations were strongly inversely correlated with CHD events (Birjmohun et al., 2007).
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