Description
Monoclonal Antibodies to CHI3L1 Clone4(13F3-1) | NBP0223-4 | Bioworld
Host: mouse
Expression: N/A
Tag: N/A
Isotype: Not Determined
Determination Method: N/A
Application: N/A
General Information: YKL-40, also known as Chitinase-3-like protein 1 (CHI3L1), is a secreted glycoprotein encoded by the CHI3L1 gene. Unlike other members of the chitinase-like protein family, YKL-40 is not an active chitinase. It is produced by activated macrophages, chondrocytes, neutrophils, and synovial cells. It is a pro-inflammatory molecule that contributes to the progression of many inflammatory diseases, including fibrosis, neurodegenerative disease, breast, lung, prostate, liver, bladder, colon, and other types of cancers. Levels of YKL-40 in serum and plasma in patients with various types of tumors have been reported to predict poor prognosis, and in some clinical assays YKL-40 is being used as a predictive biomarker of cancer outcome.
Recomendation: N/A
Product Buffer: PBS, pH7.4.
Purity: >95% as determined by SDS-PAGE.
Storage: Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage.
Specificity: Antibody recognizes CHI3L1
Source: N/A
Molecular weight: N/A
Note: N/A