Description
Monoclonal Antibodies to MMP-3 Clone2(5B9) | NBP0217-2 | Bioworld
Host: mouse
Expression: N/A
Tag: N/A
Isotype: Not Determined
Determination Method: N/A
Application: N/A
General Information: The matrix metalloproteinases (MMPs) are a family of proteases that target many extracellular proteins including other proteases, growth factors, cell surface receptors, and adhesion molecules. Among the family members, MMP-2, MMP-3, MMP-7, and MMP-10 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis, and apoptosis. Research studies have shown that MMP activity correlates with cancer development. One mechanism of MMP regulation is transcriptional. Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full length protein.
Recomendation: N/A
Product Buffer: PBS, pH7.4.
Purity: >95% as determined by SDS-PAGE.
Storage: Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage.
Specificity: Antibody recognizes human MMP-3
Source: N/A
Molecular weight: N/A
Note: N/A