Biotinylated Dust Mite Extract from D. farinae

Biotinylated Dust Mite Extract from D. farinae - Cat Number: 3045 From Chondrex.

Research Field: Allergy

Clonality: N/A

Cross-Reactivity:

Host Origin: N/A

Applications: N/A

Isotype: N/A

Detection Range: N/A

Sample Type: N/A

Concentration: N/A

Immunogen:

PRODUCT SPECIFICATIONS

DESCRIPTION: Biotinylated House Dust Mite extract from Dermatophagoides farinae.
House Dust Mite (HDM) is a common asthma allergen that more than 85% of asthma patients
are sensitive to. Two major house dust mite species, Dermatophagoides pteronyssinus (Der p)
and Dermatophagoides farinae (Der f), were found in asthma pathogenesis studies. The mites
contain more than 20 types of HDM allergens; group 1 (Der 1) and group 2 (Der 2) allergens
dominate overall allergic responses in patients and are the most commonly researched
allergens (1-3).
NOTE: House Dust Mite extract has a unique composition depending on the raw mite materials.
The reactivity of this product may differ from batch to batch.
APPLICATION: Use to detect anti-HDM antibodies as well as to study the localization and metabolism of HDM.
Chondrex, Inc. recommends pairing biotinylated HDM with a streptavidin conjugated probe
(enzyme or fluorochrome)
QUANTITY: 0.1 mg protein
FORM: Lyophilized powder
STORAGE: -20⁰C
STABILITY: 2 years
NOTES: N/A

REFERENCES:

1. W. R. Thomas, W. Smith, House-dust-mite allergens. Allergy 53, 821-832 (1998).
2. A. Custovic, S. Taggart, H. Francis, M. Chapman, A. Woodcock, Exposure to house dust mite allergens and the clinical activity of asthma. J Allergy Clin Immunol 98, 64-72 (1996).
3. A. Jacquet, The role of innate immunity activation in house dust mite allergy. Trends Mol
Med 17, 604-11 (2011).