Muramyl Di peptide, MDP, 2 mg

Muramyl Di peptide, MDP, 2 mg - Cat Number: 9065 From Chondrex.

Research Field: Arthritis

Clonality: N/A

Cross-Reactivity:

Host Origin: N/A

Applications: N/A

Isotype: N/A

Detection Range: N/A

Sample Type: N/A

Concentration: N/A

Immunogen:

DESCRIPTION: Mycobacterium tuberculosis, the main component in Complete Freund’s Adjuvant, is used to
up-regulate

the Th1 immune response in animals. Muramyl dipeptide (MDP) is an
immunoreactive synthetic peptide which mimics the active component in the cell wall of
Mycobacterium tuberculosis (1).
APPLICATION: Use as an adjuvant for immunization to produce antibodies and develop adjuvant-induced
arthritis and collagen-induced arthritis in rats (2).
QUANTITY: 2 mg
FORM: Lyophilized powder
MOLECULAR WEIGHT: 492.48
PURITY: >98% by thin layer chromatography
STORAGE: 4°C in the dark for lyophilized form and -20°C for solution form (Avoid multiple freeze/thaw
cycles).
STABILITY: 1 year in lyophilized form
NOTES: N/A
REFERENCES:
1. F. Ellouz, A. Adam, R. Ciorbaru, E. Lederer, Minimal structural requirements for adjuvant
activity of bacterial peptidoglycan derivatives. Biochem Biophys Res Commun 59, 1317-
25 (1974).
2. S Kleinau, H Erlandsson, L. Klareskog. Percutaneous exposure of adjuvant oil causes
arthritis in DA rats. Clin Exp Immunol 96:281-284, 1994.