Anti Human C1 Esterase Inhibitor made in goat | 110003

A single chain glycoprotein which inhibits C1, C1r, C1s, plasma kallikrein, Factors XIa. XIIa, and plasmin. Present in plasma at 16-33 mg per 100 ml. C1 esterase inhibitor deficiency is a rare condition resulting in facial swelling and abdominal cramping. Usually the condition is hereditary, though it may also occur when the C1EI is non-functional.

Ref: Salvesen, G.S et al. 1985. J. Biol. Chem. 260, 2432.

Product Citations:
Lee, Kyoung Geun, Haneulnari Lee, Jeong Mi Ha, Young Kyung Lee, Hee Jung Kang, Chung‐Gyu Park, and Sang Joon Kim. "Increased human tumor necrosis factor‐α levels induce procoagulant change in porcine endothelial cells in vitro."Xenotransplantation 19, no. 3 (2012): 186-195

Kang, Hee Jung, Haneulnari Lee, Jeong-mi Ha, Jae-il Lee, Jun-Seop Shin, Ki-Yong Kim, Ji Yoon Park et al. "The Role of the Alternative Complement Pathway in Early Graft Loss After Intraportal Porcine Islet Xenotransplantation." Transplantation (2014)

Synonym: Complement C1 esterase inhibitor, Esterase inhibitor C-1