Anti-sodium Iodide Symprter
Description
The sodium iodide symporter (NIS) is an ion pump that actively transports iodide across the basolateral membrane into thyroid epithelial cells (1, 2). This is important step in the process of iodide organificaton and the formation of triiodothyronine and thyroxine (3). Mouse Anti-Human Sodium-Iodide Symporter Monoclonal IgG1 Kappa
Background
The sodium iodide symporter (NIS) is an ion pump that actively transports iodide across the basolateral membrane into thyroid epithelial cells (1, 2). This is important step in the process of iodide organificaton and the formation of triiodothyronine and thyroxine (3).
Host
Mouse
Clone
FP5
Isotype
IgG1 kappa
Immunogen
Mannose binding protein hNIS fusion (AA468-643)
Synonyms
NIS Antibody, SLC5A5 Antibody, solute carrier family 5 Antibody, Na (+)I(-) cotransporter Antibody
Specificity
Detects ~97kDa, non-glycosylated version at 68kDa. Other minor bands associated with hNIS at 160kDa, and degradation products at ~30 kDa, and ~15kDa.
Reactivity
Human, Mouse, Rat
Applications
AM, ICC, IF, IHC, WB
Form
Purified, in PBS pH7.4, 50% glycerol, 0.09% sodium azide
SwissProt
Q92911
Gene ID
NP_000444.1. 6528
Uniprot
Q92911
