Anti- RET Finger Protein (RFP) Rabbit IgG Affinity Purify | 18791
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- SKU:
- 18791
- Availability:
- In Stock
- Application:
- WB, IP, IHC, ICC
- Purification Method:
- Purified with antigen peptide
- Storage Condition:
- 2 - 8℃
Description
Anti- RET Finger Protein (RFP) Rabbit IgG Affinity Purify | 18791
RET finger protein (RFP) belongs to the large B-box RING finger protein family and is known to become oncogenic by fusion with RET tyrosine kinase. Although RFP is reported to be a nuclear protein that is present in the nuclear matrix, its function is largely unknown. RFP interacts with Enhancer of Polycomb (EPC) and strongly represses the gene transcription. Yeast two-hybrid assays revealed that the coiled-coil domain of RFP was associated with the EPcA domain and the carboxyl-terminal region of EPC. RFP may be involved in the epigenetic gene silencing mechanism cooperating with Polycomb group protein.
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