FADD Polyclonal Antibody | GRP253

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SKU:
GRP253
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Size:
100 μl
  • FADD Polyclonal Antibody | GRP253
  • FADD Polyclonal Antibody | GRP253
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Description

FADD Polyclonal Antibody | GRP253

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity).

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