Vasculitis Screen | GCP-CAP

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SKU:
GCP-CAP
Availability:
In Stock
Size:
96 wells
Read-out of results:
Qualitative
Assay time:
40 min
Detection system:
ALP/pNPP read at 405 nm
Regulatory status:
IVD, CE labeled
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Description

Vasculitis Screen | GCP-CAP

The Wieslab® Vasculitis Screening Test Kit is an ELISA for the qualitative detection of antibodies to glomerular basement membrane (GBM), Proteinase-3 (PR3) and Myeloperoxidase (MPO) in human sera.

The assay is used to detect antibodies in a single serum specimen and the results of the assay are to be used as an aid to the diagnosis of reno-pulmonary syndromes and rapidly progressive glomerulonephritis, especially Goodpasture syndrome (GP), Wegener’s granulomatosis (WG/ granulomatosis with polyangiitis) and microscopic polyangiitis (MP).

What's in the box?

  • One frame with 96 wells coated with purified GBM antigen (Bovine), monoclonal anti-proteinase 3/proteinase 3 (Human Neutrophil) and monoclonal anti-myeloperoxidase/myeloperoxidase (Human Neutrophil) and control wells with monoclonal mouse antibody or human serum albumin: one lid sealed in a foil pack with a dry pack.
  • 3 mL negative control (NC) containing human serum in diluent (green colour)
  • 3 mL positive control (PC) containing human serum in diluent (red colour)
  • 13 mL conjugate containing alkaline phosphatase-labelled (Goat) antibodies to human IgG (blue colour)
  • 32 mL Diluent (Dil) containing PBS (red colour)
  • 13 mL Substrate pNPP
  • 13 mL Stop Solution
  • 30 mL Wash solution 30x concentrated

All reagents in the kit are ready for use except wash solution and should be stored at + 2-8° C.

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