Bionized NanoFerrite Particles (BNF Particles)

• Are manufactured using the core-shell process and have a core of 75-80% (w/w) magnetite and a shell of dextran or hydroxyethyl starch,
• Are available with diameters of 80 nm and 100 nm,
• Are thermally blocked at room temperature and show specific interactions with alternating magnetic fields (Dennis et al. 2008 and 2009; Krycka et al., 2011; Bordelon et al., 2011),
• 100 nm – BNF particles can be separated with conventional permanent magnets,
• 80 nm – BNF particles must be separated in a high gradient magnetic field or on a strong permanent magnet for several hours,
• Are offered with the surface functionalities OH (plain), NH2, PEG-NH2, COOH and PEG-COOH for the covalent binding of proteins, antibodies or other molecules,
• Are available with covalently bound proteins (streptavidin, protein A),
• Can be conjugated with special antibodies on request,
• Can be easily filtered through 0.22 µm filters.