236 results for 'CRISPR-Cas9'

ABMGood | asCpf1 Nuclease NLS Protein | K188 Using Cpf1 (a.k.a. Cas12a) in your CRISPR experiment offers several advantages over other CRISPR-associated nucleases. Due to the T-rich PAM sequence...

abm | NOD1 Stable Knockout AGS (41H8) Cell Line | T6188CRISPR/Cas9 gene editing was used to generate NOD1 KO clones. For this, AGS cells were transformed with vectors expressing “Cas9 nickase”...

abm | HMGN1-HMGN2 Double KO Stable U2OS Cell Line (1-6) | T6428HMGN1/HMGN2 double knock-out (dKO) cells were generated by CRISPR-Cas9-mediated genome editing. U2OS cells were co-transfected with...

abm | HMGN1-HMGN2 Double KO Stable U2OS Cell Line (1-5) | T6427HMGN1/HMGN2 double knock-out (dKO) cells were generated by CRISPR-Cas9-mediated genome editing. U2OS cells were co-transfected with...

abm | PIWIL1 Knockout Stable AGP01 Cell Line | T6410PIWIL1 was knocked out of the AGP01 cells via CRISPR/Cas9. May be used to study the potential functions of the PIWIL1 gene...

abm | SIRT1 Knockout Stable 293T Cell Line | T3176SIRT1 Knockout Stable 293T Cell Line was established via CRISPR/Cas9 mediated knockout of the endogenously expressing SIRT1 gene also known as...

abm | TP53 Stable Knockout K9 Fetus 1 Cell Line | T6405TP53 was knocked out of the K9 Fetus 1 cells via CRISPR/Cas9. May be used as a cellular system to examine novel oncogenic functions, and...

abm | CBFβ Stable Knockout HepG2 Cell Line | T6161CBFβ is the non-DNA-binding subunit of the core binding factor (CBF) transcription factor. Derived from HepG2 cells, CBFβ was knocked out using...

abm | SIRT1 Knockout Stable RKO Cell Line | T3172SIRT1 Knockout Stable RKO Cell Line was established via CRISPR/Cas9 mediated knockout of the endogenously expressing SIRT1 gene also known as Sirtuin...

abm | SIRT1 Knockout Stable DLD-1 Cell Line | T3174SIRT1 Knockout Stable DLD-1 Cell Line was established via CRISPR/Cas9 mediated knockout of the endogenously expressing SIRT1 gene also known as...

abm | PML-SP100 Stable Double Knockout HEp-2 Cell Line | T6136PML−/− cells, generated using CRISPR/Cas9 human epithelial type 2 (HEp-2) cells. Considered to originate from a human laryngeal...

abm | CYP3A5 Double Deleted HuH-7 Cell Line | T6346Cells were derived from HuH-7 cells. Cells were then genetically modified using CRISPR/Cas9 method with two guide RNAs to homozygously delete...

abm | FLNC Stable Knockout Human A2780 Cell Line | T9503FLNC Stable Knockout Human A2780 Cell Line is established via CRISPR/Cas9 mediated frameshift mutation of the FLNC gene (NM_001458) using the...

abm | CYP3A5 Single Deleted HuH-7 Cell Line | T6347Cells were derived from HuH-7 cells. Cells were then genetically modified using CRISPR/Cas9 method with two guide RNAs to heterozygously delete...

abm | GAB1 Stable Knockout Human 8505c Cell Line | T9501GAB1 Stable Knockout Human 8505c Cell Line is established via CRISPR/Cas9 mediated frameshift mutation of the GAB1 gene (NM_002039) using the...

abm | LIN28B Stable Knockout Human A2780 Cell Line | T9506LIN28B Stable Knockout Human A2780 Cell Line is established via CRISPR/Cas9 mediated frameshift mutation of the LIN28B gene (NM_001004317)...

abm | NLK Stable Knockout Human A549 Cell Line | T9510NLK Stable Knockout Human A549 Cell Line is established via CRISPR/Cas9 mediated frameshift mutation of the NLK gene (NM_016231) using the...

abm | Pax6 KnockOut U251N Cell Line | T6167CRISPR-Cas9 was utilized to knockout PAX6 from the U251N cells to establish Pax6 KnockOut U251N Cell Line (2.10 KO cells). Knockout was verified via...

abm | CYP3A5 Point Mutation HuH-7 Cell Line | T6348Cells were derived from HuH-7 cells. Cells were genetically modified using CRISPR/Cas9 method with 1 guide RNA and HDR template to heteroygously...

abm | JWA Stable Knockout Human MHCC97L Cell Line | T9504JWA Stable Knockout Human MHCC97L Cell Line is established via CRISPR/Cas9 mediated frameshift mutation of the JWA gene (NM_006407) using the...

abm | FRK Stable Knockout Human H1299 Cell Line | T9505FRK Stable Knockout Human H1299 Cell Line is established via CRISPR/Cas9 mediated frameshift mutation of the FRK gene (NM_002031) using the...

abm | GALE Stable Knockout HEK293T (Clone 4) Cell Line | T6150The GALE gene encodes UDP-galactose-4 epimerase which operates in the Leloir pathway, the primary pathway for galactose metabolism. This...

abm | MAPRE1 Doxycycline Inducible Knockout HeLa Cell Line | T6173This human cell line stably expresses single guide RNA (sgRNA) targeting an early exon of MAPRE1 (microtubule-associated protein...

abm | MAPRE1-MAPRE3 Doxycycline Inducible Double Knockout HeLa Cell Line | T6174This human cell line stably expresses single guide RNA (sgRNA) targeting an early exon of MAPRE1...

Fast Genomic DNA Extraction from Cells and Tissues | TBS6008 Fast DNA extraction kit provides a simple and rapid method to isolate the genomic DNA from tissues or cells for PCR amplification,...

abm | IP6K2--- Stable HCT116 Cell Line | T6350To study the role that PP-IPs play in mammalian phosphate homeostasis, researchers generated cells devoid of this small molecule. CRISPR was used to...

abm | ADRM1 Stable Knockout HCT116 (Clone B11) Cell Line | T6162ADRM1 or Adhesion regulating molecule 1, is a component of the proteosome and ubiquitin receptor that recruits the deubiquitinating...

abm | IP6K1--- & IP6K2--- Stable HCT116 Cell Line | T6351To study the role that PP-IPs play in mammalian phosphate homeostasis, researchers generated cells devoid of this small molecule. CRISPR was...

Description T7 Endonuclease I, a stable homodimer of identical 149 amino acid subunits (1) is the product of a recombinant gene in E. coli . Double-stranded breaks (DSBs) generated by...

abm | IP6K1--- Stable HCT116 Cell Line | T6349To study the role that PP-IPs play in mammalian phosphate homeostasis, researchers generated cells devoid of this small molecule. CRISPR was used to...

Description T7 Endonuclease I, a stable homodimer of identical 149 amino acid subunits (1) is the product of a recombinant gene in E. coli . Double-stranded breaks (DSBs) generated by...

abm | RFP Stably Expressing HEK293 Cell Line (Safe Harbor Site) | T3700HEK293 cells stably expressing RFP using CRISPR Knock In Technology at the Safe Harbor Site (AAVS1) ...

abm | Stable Mgat2 Knockout K16 CHO Cell Line | T6008Using CRISPR technology Mgat2 was silenced from the K16 CHO cells to generate a glycosylation mutant cell line which expresses hybrid type...